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CS-W001157 4
Total: USD 88.00

4-Bromo-2-fluoro-6-nitrobenzaldehyde

  • CAS No. 1698028-22-6

  • Cat. No. CS-0256090
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-fluoro-6-nitrobenzaldehyde|CS-0256090

Structure of 1698028-22-6

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General Information

  • CAS No. 1698028-22-6
  • Cat. No. CS-0256090
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₃BrFNO₃
  • Molecular Weight 248.01
  • Synonym(s) None
  • SMILES O=CC1=C([N+]([O-])=O)C=C(Br)C=C1F

Description

4-Bromo-2-fluoro-6-nitrobenzaldehyde features a trifunctional aromatic core bearing bromo, fluoro, and nitro substituents ortho to the aldehyde group. This electron-deficient scaffold enables direct coupling in cross-coupling reactions and serves as a key building block for advanced pharmaceutical intermediates and functional materials.

Application

4-Bromo-2-fluoro-6-nitrobenzaldehyde serves as a versatile building block in the synthesis of pharmaceutical intermediates and functionalized heterocycles. Its ortho-fluoro and para-bromo substituents enable selective metal-catalyzed coupling reactions, while the aldehyde and nitro groups offer complementary reactivity for sequential transformations. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for multi-step synthetic sequences in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   60.21
  • LogP   2.3089
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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