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CS-W001157 4
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H-D-Orn(Z)-OH

  • CAS No. 16937-91-0

  • Cat. No. CS-W022744
  • Molecule weight266.29
  • Purity≥97%
  • MDL No.MFCD00063115

*For research and further manufacturing use only, not for direct human use.

H-D-Orn(Z)-OH|CS-W022744

Structure of 16937-91-0

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General Information

  • CAS No. 16937-91-0
  • Cat. No. CS-W022744
  • Purity ≥97%
  • MDL No. MFCD00063115
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈N₂O₄
  • Molecular Weight 266.29
  • Synonym(s) (R)-2-Amino-5-(((benzyloxy)carbonyl)amino)pentanoic acid
  • SMILES O=C(O)[C@H](N)CCCNC(OCC1=CC=CC=C1)=O

Description

H-D-Orn(Z)-OH is a D-configured ornithine derivative featuring a Z-configured olefinic bond and a terminal hydroxyl group. This configuration enhances metabolic stability while maintaining bioactive conformation, enabling efficient incorporation into peptide scaffolds under standard coupling conditions.

Application

H-D-Orn(Z)-OH serves as a stable, bench-ready building block for the synthesis of peptidomimetics and bioactive oligomers. The Z-protected diamino acid facilitates selective coupling in solid-phase and solution-phase peptide synthesis, enabling efficient incorporation into complex scaffolds. Its D-stereoisomer offers enhanced metabolic stability, while the orthogonal protection supports sequential functionalization in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   101.65
  • LogP   1.1049
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   7

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