Lot numbers can be found on the outside label of a product:
1-(2-Amino-5-chlorophenyl)ethanone
-
CAS No. 1685-19-4
- Cat. No. CS-W005834
- Purity≥97%
- MDL No.MFCD07434611
*For research and further manufacturing use only, not for direct human use.
Structure of 1685-19-4
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 1685-19-4
- Cat. No. CS-W005834
- Purity ≥97%
- MDL No. MFCD07434611
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₈ClNO
- Molecular Weight 169.61
- Synonym(s) Ethanone,1-(2-amino-5-chlorophenyl)-1-(2-aMino-5-chlorophenyl)ethan-1-one(2-AMino-5-chlorophenyl)ethanone
- SMILES CC(=O)C1=C(N)C=CC(Cl)=C1
Description
1-(2-Amino-5-chlorophenyl)ethanone features a chlorinated aromatic ring paired with an amino group and a ketone functionality, enabling direct integration into pharmaceutical intermediates. The electron-rich amine facilitates coupling reactions, while the para-chloro substituent enhances reactivity in electrophilic transformations. This compound serves as a key scaffold for targeted synthesis in medicinal chemistry applications.
Application
1-(2-Amino-5-chlorophenyl)ethanone serves as a key building block in the synthesis of heterocyclic scaffolds and pharmaceutical intermediates. Its ortho-amino and chloro substituents enable diverse coupling reactions and cyclization pathways, while the acetyl group offers a handle for further functionalization. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
Synthesis
-
Route1
-
In-stock
18640-60-3 - ~88%
-
In-stock
1685-19-4
References
-
Meyer, Adam Gerhard; Winzenberg, Kevin Norman; Sawutz, David G.; Liepa, Andris Juris Patent: US2006/63841 A1, 2006 ; Location in patent: Page/Page column 24; 4/12 ;
-
-
Route2
-
In-stock
150879-48-4 -
917-54-4 - ~%
-
In-stock
1685-19-4
References
-
US2007/88071 A1, ; Page/Page column 33 ; US 20070088071 A1
-
-
Route3
-
106-47-8
-
75-05-8
- ~22%
-
In-stock
1685-19-4
References
-
Nittoli, Thomas; Curran, Kevin; Insaf, Shabana; DiGrandi, Martin; Orlowski, Mark; Chopra, Rajiv; Agarwal, Atul; Howe, Anita Y. M.; Prashad, Amar; Floyd, M. Brawner; Johnson, Bernard; Sutherland, Alan; Wheless, Karen; Feld, Boris; O'Connell, John; Mansour, Tarek S.; Bloom, Jonathan Journal of Medicinal Chemistry, 2007 , vol. 50, # 9 p. 2108 - 2116
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 43.09
- LogP 2.1248
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 1-(2-Amino-5-chlorophenyl)ethanone sigma1-(2-Amino-5-chlorophenyl)ethanone manufacturer1-(2-Amino-5-chlorophenyl)ethanone price1-(2-Amino-5-chlorophenyl)ethanone structure1-(2-Amino-5-chlorophenyl)ethanone SDSbuy 1-(2-Amino-5-chlorophenyl)ethanone1-(2-Amino-5-chlorophenyl)ethanone supplier1-(2-Amino-5-chlorophenyl)ethanone uses1-(2-Amino-5-chlorophenyl)ethanone molecular weightprice of 1-(2-Amino-5-chlorophenyl)ethanone1-(2-Amino-5-chlorophenyl)ethanone chemical name formula of 1-(2-Amino-5-chlorophenyl)ethanone