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CS-W001157 4
Total: USD 88.00

2′-O-(2-Methoxyethyl)adenosine

  • CAS No. 168427-74-5

  • Cat. No. CS-0100781
  • Purity≥98%
  • MDL No.MFCD02682961

*For research and further manufacturing use only, not for direct human use.

2′-O-(2-Methoxyethyl)adenosine|CS-0100781

Structure of 168427-74-5

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General Information

  • CAS No. 168427-74-5
  • Cat. No. CS-0100781
  • Purity ≥98%
  • MDL No. MFCD02682961
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₉N₅O₅
  • Molecular Weight 325.32
  • Synonym(s) None
  • SMILES O[C@@H]1[C@@H](OCCOC)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1CO

Description

2′-O-(2-Methoxyethyl)adenosine features a modified ribose moiety that enhances nuclease resistance and cellular uptake. This derivative exhibits improved stability in biological systems while retaining recognition by adenosine receptors, enabling prolonged signaling activity in vitro and in vivo.

Synthesis

  • Route1
    • null|null
      168427-73-4
    • ~92%
    • In-stock
      2′-O-(2-Methoxyethyl)adenosine|CS-0100781
      168427-74-5

    References

    • Martin Helvetica Chimica Acta, 1995 , vol. 78, # 2 p. 486 - 504
  • Route2

    References

    • Nucleosides, Nucleotides and Nucleic Acids, , vol. 26, # 10-12 p. 1237 - 1240
  • Route3

    References

    • Helvetica Chimica Acta, , vol. 78, # 2 p. 486 - 504

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   137.77
  • LogP   -1.3093
  • H_Acceptors   10
  • H_Donors   3
  • Rotatable_Bonds   6

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Key Words

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