Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-(5-Bromo-2-methoxyphenyl)ethan-1-one

  • CAS No. 16740-73-1

  • Cat. No. CS-0100836
  • Purity≥96%
  • MDL No.MFCD03789141

*For research and further manufacturing use only, not for direct human use.

1-(5-Bromo-2-methoxyphenyl)ethan-1-one|CS-0100836

Structure of 16740-73-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 16740-73-1
  • Cat. No. CS-0100836
  • Purity ≥96%
  • MDL No. MFCD03789141
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉BrO₂
  • Molecular Weight 229.07
  • Synonym(s) 5-Bromo-2-methoxyacetophenone
  • SMILES CC(C1=CC(Br)=CC=C1OC)=O

Description

This brominated acetophenone derivative features a methoxy-substituted aryl ring and a reactive ketone group, enabling direct integration into cross-coupling and functionalization workflows. The para-bromo substitution enhances electrophilicity for palladium-catalyzed reactions, while the methoxy group provides moderate electron donation and improved solubility in polar organic solvents.

Application

1-(5-Bromo-2-methoxyphenyl)ethan-1-one serves as a versatile building block in cross-coupling reactions and heterocycle synthesis, enabling efficient construction of biaryl and substituted aromatic scaffolds. The bromo group facilitates palladium-catalyzed coupling, while the methoxy functionality offers moderate electron-donating character and orthogonal handle for further modification. Bench-stable and readily purified by column chromatography, it functions reliably in standard synthetic workflows for medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • In-stock
      1-(5-Bromo-2-hydroxyphenyl)ethanone|CS-W007495
      1450-75-5
    • null|null
      74-88-4
    • ~99%
    • In-stock
      1-(5-Bromo-2-methoxyphenyl)ethan-1-one|CS-0100836
      16740-73-1

    References

    • Shim, Yi Sup; Kim, Ki Chul; Chi, Dae Yoon; Lee, Keun-Hyeung; Cho, Hyeongjin Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 15 p. 2561 - 2563
  • Route2

    References

    • Pravst, Igor; Zupan, Marko; Stavber, Stojan Tetrahedron Letters, 2006 , vol. 47, # 27 p. 4707 - 4710
  • Route3

    References

    • Drug Metabolism and Disposition, , vol. 40, # 10 p. 2002 - 2008,7

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P280-P301+P330+P331

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.6603
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-(5-Bromo-2-methoxyphenyl)ethan-1-one sigma1-(5-Bromo-2-methoxyphenyl)ethan-1-one manufacturer1-(5-Bromo-2-methoxyphenyl)ethan-1-one price1-(5-Bromo-2-methoxyphenyl)ethan-1-one structure1-(5-Bromo-2-methoxyphenyl)ethan-1-one SDSbuy 1-(5-Bromo-2-methoxyphenyl)ethan-1-one1-(5-Bromo-2-methoxyphenyl)ethan-1-one supplier1-(5-Bromo-2-methoxyphenyl)ethan-1-one uses1-(5-Bromo-2-methoxyphenyl)ethan-1-one molecular weightprice of 1-(5-Bromo-2-methoxyphenyl)ethan-1-one1-(5-Bromo-2-methoxyphenyl)ethan-1-one chemical name formula of 1-(5-Bromo-2-methoxyphenyl)ethan-1-one
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label