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CS-W001157 4
Total: USD 88.00

4,5-Diamino-6-hydroxypyrimidine

  • CAS No. 1672-50-0

  • Cat. No. CS-B0340
  • Purity≥95%
  • MDL No.MFCD00006114

*For research and further manufacturing use only, not for direct human use.

4,5-Diamino-6-hydroxypyrimidine|CS-B0340

Structure of 1672-50-0

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General Information

  • CAS No. 1672-50-0
  • Cat. No. CS-B0340
  • Purity ≥95%
  • MDL No. MFCD00006114
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₄O
  • Molecular Weight 126.12
  • Synonym(s) 5,6-Diamino-4-pyrimidinol
  • SMILES O=C1C(N)=C(N)N=CN1

Description

4,5-Diamino-6-hydroxypyrimidine delivers a bifunctional pyrimidine scaffold featuring two amino groups and a hydroxyl moiety at the 4,5,6-positions. This arrangement enables direct integration into nucleoside analogs and heterocyclic frameworks via straightforward coupling reactions. The compound exhibits enhanced solubility in aqueous and polar organic solvents, facilitating use in synthetic workflows requiring mild reaction conditions.

Application

4,5-Diamino-6-hydroxypyrimidine serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrimidine-based scaffolds through standard functional group transformations. Its ortho-diamino and hydroxyl functionalities facilitate metal-catalyzed couplings, cyclizations, and derivatization under mild conditions. The compound exhibits good bench stability and compatibility with common protecting groups, making it suitable for iterative synthesis workflows in medicinal chemistry and agrochemical development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   97.79
  • LogP   -1.0657
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   0

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