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CS-W001157 4
Total: USD 88.00

4,4'-Bis(hydroxymethyl)biphenyl

  • CAS No. 1667-12-5

  • Cat. No. CS-W009311
  • Purity≥98%
  • MDL No.MFCD00016713

*For research and further manufacturing use only, not for direct human use.

4,4'-Bis(hydroxymethyl)biphenyl|CS-W009311

Structure of 1667-12-5

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General Information

  • CAS No. 1667-12-5
  • Cat. No. CS-W009311
  • Purity ≥98%
  • MDL No. MFCD00016713
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₄O₂
  • Molecular Weight 214.26
  • Synonym(s) (4'-HYDROXYMETHYL-BIPHENYL-4-YL)-METHANOL
  • SMILES OCC1=CC=C(C2=CC=C(CO)C=C2)C=C1

Description

It is an active pharmaceutical intermediate. Condensation of amino carboxyalkyl derivative of 4,5,6,7-tetrahydrobenzo[b]thiophene with salicylaldehyde yielded a potentially tridentate Schiff base (HSAT), which formed a series of copper(II) complexes. Reaction of ethyl 2-diazo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 1 with 3-iminobutyronitrile 2 gave the hydrazone derivative.

Synthesis

  • Route1

    References

    • ENIRICERCHE S.p.A. Patent: EP469682 A1, 1992 ;
  • Route2
    • In-stock
      Dimethyl biphenyl-4,4'-dicarboxylate|CS-0100928
      792-74-5
    • null|null
      7732-18-5
    • ~99%
    • In-stock
      4,4'-Bis(hydroxymethyl)biphenyl|CS-W009311
      1667-12-5

    References

    • Eniricerche S.p.A. Patent: US5166380 A1, 1992 ;
  • Route3

    References

    • Szunerits, Sabine; Utley, James H. P.; Nielsen, Merete F. Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 4 p. 669 - 675

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   2.3382
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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