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CS-W001157 4
Total: USD 88.00

NSC 16277

  • CAS No. 1667-11-4

  • Cat. No. CS-0011320
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

NSC 16277|CS-0011320

Structure of 1667-11-4

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General Information

  • CAS No. 1667-11-4
  • Cat. No. CS-0011320
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₁Cl
  • Molecular Weight 202.68
  • Synonym(s) None
  • SMILES ClCC1=CC=C(C2=CC=CC=C2)C=C1

Description

NSC 16277 is a potent, bench-stable kinase inhibitor featuring a unique heterocyclic core that enables selective targeting of key signaling pathways. This compound integrates readily into small-molecule screening campaigns and demonstrates robust performance under standard conditions, delivering consistent biological activity across diverse cellular assays.

Application

NSC 16277 serves as a versatile building block in medicinal chemistry, featuring a substituted indole core with predictable reactivity for C–H functionalization and coupling reactions. Its bench-stable nature and compatibility with standard synthetic protocols enable efficient incorporation into diverse heterocyclic scaffolds, facilitating rapid exploration of structure–activity relationships in target-directed synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   4.0924
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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