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CS-W001157 4
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(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride

  • CAS No. 16652-71-4

  • Cat. No. CS-W012787
  • Purity≥97%
  • MDL No.MFCD00039002

*For research and further manufacturing use only, not for direct human use.

(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride|CS-W012787

Structure of 16652-71-4

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General Information

  • CAS No. 16652-71-4
  • Cat. No. CS-W012787
  • Purity ≥97%
  • MDL No. MFCD00039002
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆ClNO₂
  • Molecular Weight 241.72
  • Synonym(s) None
  • SMILES O=C(OCC1=CC=CC=C1)[C@]2([H])CCCN2.Cl

Description

Extensive applications in peptide chemistry and used as a chiral auxiliary in the asymmetric Diels-Alder reaction.

Synthesis

  • Route1
    • null|null
      37787-77-2
    • ~74%
    • In-stock
      (S)-Benzyl pyrrolidine-2-carboxylate hydrochloride|CS-W012787
      16652-71-4

    References

    • HANMI HOLDINGS CO., LTD.; BAE, In Hwan; BYUN, Eun Young; JU, Hae Kyoung; SONG, Ji Young; JUNG, Seung Hyun; JUN, Mi Ae; KIM, Ho Seok; JUNG, Young Hee; SHIM, Mi Yon; AHN, Young Gil; KIM, Maeng Sup Patent: WO2012/30160 A2, 2012 ; Location in patent: Page/Page column 22 ;
  • Route2

    References

    • Sellanes, Diver; Campot, Francisco; Nunez, Ivana; Lin, Gerardo; Esposito, Pablo; Dematteis, Sylvia; Saldana, Jenny; Domilnguez, Laura; Manta, Eduardo; Serra, Gloria Tetrahedron, 2010 , vol. 66, # 29 p. 5384 - 5395
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 81, p. 5803

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.9036
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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