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Structure of 166247-63-8
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7-Deaza-2'-deoxy-7-iodoadenosine features a iodinated purine scaffold with enhanced stability and orthogonal reactivity. This modified nucleoside integrates seamlessly into oligonucleotide synthesis workflows, enabling site-specific incorporation of iodine for downstream functionalization via cross-coupling. The 7-deaza substitution reduces electronic perturbation while maintaining base-pairing fidelity, making it ideal for probing DNA structure-function relationships.
7-Deaza-2'-deoxy-7-iodoadenosine serves as a versatile building block for nucleoside analog synthesis, enabling site-specific functionalization via palladium-catalyzed cross-coupling reactions. The iodine substituent at the 7-position provides high reactivity and compatibility with standard coupling protocols, while the 2'-deoxy modification enhances metabolic stability. This compound facilitates efficient access to modified adenosine scaffolds relevant to antiviral and anticancer research, offering reliable bench stability and straightforward purification.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: