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tert-Butyl (S)-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)carbamate

  • CAS No. 166246-74-8

  • Cat. No. CS-0200105
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (S)-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)carbamate|CS-0200105

Structure of 166246-74-8

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General Information

  • CAS No. 166246-74-8
  • Cat. No. CS-0200105
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈N₂O₃
  • Molecular Weight 262.30
  • Synonym(s) tert-Butyl [(3S)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]carbamate
  • SMILES CC(C)(OC(N[C@H]1CC2=CC=CC=C2NC1=O)=O)C

Synthesis

  • Route1

    References

    • Sher, Philip M.; Sun, Chongqing; Sulsky, Richard B.; Wu, Gang; Ewing, William R. Patent: US2005/9870 A1, 2005 ; Location in patent: Page 17 ; US 20050009870 A1
  • Route2

    References

    • Ross, Andrew J.; Lang, Hannah L.; Jackson, Richard F. W. Journal of Organic Chemistry, 2010 , vol. 75, # 1 p. 245 - 248
  • Route3

    References

    • Birch, Alan M.; Kenny, Peter W.; Oikonomakos, Nikos G.; Otterbein, Ludovic; Schofield, Paul; Whittamore, Paul R.O.; Whalley, Dave P. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 2 p. 394 - 399

Safety Information

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Computational Chemistry Data

  • TPSA   67.43
  • LogP   2.0745
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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