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CS-W001157 4
Total: USD 88.00

3-(Diphenylphosphino)propan-1-amine

  • CAS No. 16605-03-1

  • Cat. No. CS-W018334
  • Purity≥97%
  • MDL No.MFCD00233832

*For research and further manufacturing use only, not for direct human use.

3-(Diphenylphosphino)propan-1-amine|CS-W018334

Structure of 16605-03-1

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General Information

  • CAS No. 16605-03-1
  • Cat. No. CS-W018334
  • Purity ≥97%
  • MDL No. MFCD00233832
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₈NP
  • Molecular Weight 243.29
  • Synonym(s) 3-(Diphenylphosphino)-1-propylamine
  • SMILES NCCCP(C1=CC=CC=C1)C1=CC=CC=C1

Description

Thalidomide-NH-C4-NH-Boc contains a cereblon ligand, an alkylC3, two amine groups, and a terminal tert-butyloxycarbonyl. This product is ready for conjugation to target proteins for PROTAC R&D.

Synthesis

  • Route1
    • null|null
      5032-65-5
    • ~93%
    • In-stock
      3-(Diphenylphosphino)propan-1-amine|CS-W018334
      16605-03-1

    References

    • Sakai, Toshito; Kodama, Takuya; Fujimoto, Tetsuya; Ohta, Kazuchika; Yamamoto, Iwao; Kakehi, Akikazu Journal of Organic Chemistry, 1994 , vol. 59, # 23 p. 7144 - 7147
  • Route2
    • null|null
      829-85-6
    • ~%
    • In-stock
      3-(Diphenylphosphino)propan-1-amine|CS-W018334
      16605-03-1

    References

    • Tetrahedron Letters, , vol. 46, # 36 p. 6159 - 6162
  • Route3
    • In-stock
      3-Chloropropan-1-amine hydrochloride|CS-0015792
      6276-54-6
    • null|null
      4376-01-6
    • ~80%
    • In-stock
      3-(Diphenylphosphino)propan-1-amine|CS-W018334
      16605-03-1

    References

    • Kashiwabara, Kazuo; Jung, Minho; Fujita, Junnosuke Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 8 p. 2372 - 2377

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.4681
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   5

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