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CS-W001157 4
Total: USD 88.00

cis,cis-Cyclohexanetricarboxylic acid

  • CAS No. 16526-68-4

  • Cat. No. CS-0130484
  • Purity≥97%
  • MDL No.MFCD00075294

*For research and further manufacturing use only, not for direct human use.

cis,cis-Cyclohexanetricarboxylic acid|CS-0130484

Structure of 16526-68-4

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General Information

  • CAS No. 16526-68-4
  • Cat. No. CS-0130484
  • Purity ≥97%
  • MDL No. MFCD00075294
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O₆
  • Molecular Weight 216.19
  • Synonym(s) 1,3,5-Cyclohexanetricarboxylic acid, (1.alpha.,3.alpha.,5.alpha.)-
  • SMILES O=C(O)[C@H]1C[C@H](C[C@H](C1)C(O)=O)C(O)=O

Description

4-Amino-1-butanol is a useful intermediate in a variety of organic synthesis. It is mainly used in personal-care products, preparation of water soluble cationic flocculants and ion exchange resins as well as in the preparation of beta-lactam antibiotics. It is used for the production of efficient anionic emulsifiers, nonionic polyethylene emulsions, water treatment, metal treatment and absorption of carbon dioxide gas. It is used as a pigment dispersion aid and curing agent in selected textile -resins.

Application

cis,cis-Cyclohexanetricarboxylic acid serves as a versatile, bench-stable building block for constructing complex polycyclic architectures and functionalized heterocycles. Its three carboxylic acid groups exhibit predictable reactivity in esterification, amide coupling, and decarboxylation processes, enabling efficient derivatization under standard synthetic conditions. The rigid cyclohexane scaffold provides defined stereochemistry, facilitating the synthesis of stereoselective intermediates in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • In-stock
      Benzene-1,3,5-tricarboxylic acid|CS-0010336
      554-95-0
    • ~%
    • null|null
      16526-69-5
    • In-stock
      cis,cis-Cyclohexanetricarboxylic acid|CS-0130484
      16526-68-4

    References

    • Journal of Organic Chemistry, , vol. 67, # 26 p. 9288 - 9294
  • Route2

    References

    • Journal of Organic Chemistry, , vol. 46, p. 5140 - 5143
  • Route3
    • 1,3,5-Trimethyl (1α,3α,5α)-1,3,5-cyclohexanetricarboxylate|CS-0905522
      6998-83-0
    • ~%
    • In-stock
      cis,cis-Cyclohexanetricarboxylic acid|CS-0130484
      16526-68-4

    References

    • Journal of the American Chemical Society, , vol. 76, p. 4598

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

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Computational Chemistry Data

  • TPSA   111.9
  • LogP   0.9088
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   3

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