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2-Methylsulfonylethyl bromide

  • CAS No. 16523-02-7

  • Cat. No. CS-0084612
  • Purity≥95%
  • MDL No.MFCD08274926
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Methylsulfonylethyl bromide|CS-0084612

Structure of 16523-02-7

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Description

2-Methylsulfonylethyl bromide is a reactive alkylating agent featuring a sulfonylethyl handle with enhanced stability. This bromide integrates readily into nucleophilic substitution reactions, enabling efficient functionalization of heteroatoms and aromatic systems under mild conditions. The methylsulfonyl group imparts solubility and electronic tuning, facilitating its use in synthetic intermediates for pharmaceutical and agrochemical applications.

Application

2-Methylsulfonylethyl bromide serves as a versatile electrophilic building block for C–S bond formation and sulfonamide synthesis. Its bromide functionality enables efficient alkylation of nucleophiles, while the adjacent methylsulfonyl group enhances solubility and stability under standard reaction conditions. The molecule facilitates mild, high-yielding transformations in peptide modification and heterocycle construction, offering predictable reactivity and straightforward purification—ideal for iterative synthetic sequences in medicinal chemistry and process development.

General Information

  • CAS No. 16523-02-7
  • Cat. No. CS-0084612
  • Purity ≥95%
  • MDL No. MFCD08274926
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₇BrO₂S
  • Molecular Weight 187.06
  • Synonym(s) 2-Bromoethyl Methyl Sulfone
  • SMILES O=S(CCBr)(C)=O

Computational Chemistry Data

  • TPSA   34.14
  • LogP   0.4259
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group :
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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