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Structure of 16440-97-4
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5,6-Dimethyl-2,3-dihydro-1H-inden-1-one is a sterically hindered, bench-stable ketone featuring a fused bicyclic core with methyl groups at the 5- and 6-positions. This configuration enhances its resistance to side reactions while maintaining high reactivity in transition-metal-catalyzed couplings. The electron-deficient carbonyl integrates readily into synthetic sequences requiring stable, functionalized building blocks for complex molecule assembly.
5,6-Dimethyl-2,3-dihydro-1H-inden-1-one serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted indane and indenone scaffolds. Its conjugated enone system facilitates Michael additions and asymmetric hydrogenation, while the methyl groups provide steric control and enhanced stability. The compound exhibits excellent bench stability and is compatible with common functional group transformations, making it well-suited for medicinal chemistry campaigns and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: