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CS-W001157 4
Total: USD 88.00

4-Indanol

  • CAS No. 1641-41-4

  • Cat. No. CS-W006868
  • Purity≥97%
  • MDL No.MFCD00053431

*For research and further manufacturing use only, not for direct human use.

4-Indanol|CS-W006868

Structure of 1641-41-4

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General Information

  • CAS No. 1641-41-4
  • Cat. No. CS-W006868
  • Purity ≥97%
  • MDL No. MFCD00053431
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O
  • Molecular Weight None
  • Synonym(s) 2,3-Dihydro-1H-inden-4-ol
  • SMILES C1=CC=C(C2=C1CCC2)O

Description

4-Indanol offers a rigid, fused bicyclic framework ideal for probing steric and electronic effects in medicinal chemistry. This bench-stable scaffold integrates seamlessly into bioactive molecule design, where its hydroxyl group enables direct derivatization or hydrogen bonding interactions within target binding sites.

Application

4-Indanol serves as a versatile building block in synthetic organic chemistry, enabling the construction of biologically relevant heterocyclic scaffolds. Its rigid, aromatic-indane framework offers enhanced metabolic stability and favorable pharmacokinetic properties. The phenolic hydroxyl group facilitates direct functionalization or derivatization under standard conditions, while the aliphatic ring provides a site for selective oxidation or reduction. Bench-stable and readily purified by distillation or chromatography, it functions effectively in multi-step syntheses targeting pharmaceutical intermediates and agrochemicals.

Synthesis

  • Route1

    References

    • InterMune, Inc. Patent: US2011/152246 A1, 2011 ; Location in patent: Page/Page column 118-119 ;
  • Route2

    References

    • SYMPHAR S.A. Patent: EP418064 A2, 1991 ;
  • Route3
    • null|null
      107300-32-3
    • ~77%
    • In-stock
      4-Indanol|CS-W006868
      1641-41-4

    References

    • Odedra, Arjan; Wu, Chang-Jung; Pratap, Taduri Bhanu; Huang, Chun-Wei; Ran, Ying-Fen; Liu, Rai-Shung Journal of the American Chemical Society, 2005 , vol. 127, # 10 p. 3406 - 3412

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.8809
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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