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Structure of 163622-50-2
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5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine serves as a key heterocyclic scaffold for medicinal chemistry applications. This electron-deficient purine analog integrates readily into kinase inhibitors and nucleoside analogs. The iodine substituent enables facile cross-coupling reactions, while the amine functionality supports derivatization. Bench-stable under standard conditions, this compound facilitates efficient access to bioactive molecules in drug discovery workflows.
5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine serves as a versatile building block for purine-based heterocycles, enabling palladium-catalyzed cross-coupling reactions with broad functional group tolerance. Its iodine substituent facilitates efficient C–C and C–N bond formation under standard Suzuki, Stille, or Buchwald-Hartwig conditions, while the amine functionality supports further derivatization. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for medicinal chemistry campaigns and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: