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Structure of 16357-40-7
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3-Acetyl-4-hydroxybenzoic acid features a conjugated aromatic core bearing a hydroxyl group at the para position relative to a carboxylic acid, enabling hydrogen bonding and enhanced solubility. The acetyl substituent imparts electrophilic character, facilitating coupling reactions in synthetic routes to bioactive molecules and functional materials. This compound serves as a key intermediate in pharmaceutical and agrochemical synthesis.
3-Acetyl-4-hydroxybenzoic acid serves as a versatile building block for medicinal chemistry and natural product synthesis, enabling efficient access to substituted benzene scaffolds. Its ortho-difunctionalized structure—combining a carboxylic acid and phenolic hydroxyl—facilitates selective derivatization, while the acetyl group provides a handle for further transformations such as reductive cleavage or nucleophilic substitution. The compound exhibits good bench stability and is amenable to standard purification methods, making it well-suited for use in multi-step syntheses and library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: