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7-Bromo-4-chloro-1H-imidazo[4,5-c]pyridine

  • CAS No. 163452-79-7

  • Cat. No. CS-0050080
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Bromo-4-chloro-1H-imidazo[4,5-c]pyridine|CS-0050080

Structure of 163452-79-7

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General Information

  • CAS No. 163452-79-7
  • Cat. No. CS-0050080
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrClN₃
  • Molecular Weight 232.47
  • Synonym(s) 7-bromo-4-chloro-3H-imidazo[4,5-c]pyridine
  • SMILES ClC1=C2N=CNC2=C(Br)C=N1

Description

7-Bromo-4-chloro-1H-imidazo[4,5-c]pyridine is a heterocyclic scaffold featuring bromine and chlorine substituents at electron-deficient positions, enabling direct functionalization in cross-coupling reactions. This bench-stable, moisture-tolerant core integrates readily into bioactive molecules and advanced materials, offering high reactivity under standard conditions.

Application

7-Bromo-4-chloro-1H-imidazo[4,5-c]pyridine serves as a versatile heterocyclic building block for the synthesis of pharmaceutical intermediates and functional materials. Its complementary halogenation pattern enables sequential cross-coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig transformations, with high chemoselectivity. The molecule exhibits excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.3738
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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