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CS-W001157 4
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4-Bromo-1-methyl-1H-imidazol-2-amine hydrochloride

  • CAS No. 1632286-16-8

  • Cat. No. CS-0104583
  • Purity≥95%
  • MDL No.MFCD28144834

*For research and further manufacturing use only, not for direct human use.

4-Bromo-1-methyl-1H-imidazol-2-amine hydrochloride|CS-0104583

Structure of 1632286-16-8

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General Information

  • CAS No. 1632286-16-8
  • Cat. No. CS-0104583
  • Purity ≥95%
  • MDL No. MFCD28144834
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇BrClN₃
  • Molecular Weight 212.48
  • Synonym(s) None
  • SMILES NC1=NC(Br)=CN1C.[H]Cl

Description

4-Bromo-1-methyl-1H-imidazol-2-amine hydrochloride is a bench-stable, moisture-tolerant heterocyclic building block featuring a brominated imidazole core. This compound integrates readily into transition-metal-catalyzed cross-coupling reactions, enabling efficient access to functionalized imidazole scaffolds for medicinal chemistry and materials applications.

Application

4-Bromo-1-methyl-1H-imidazol-2-amine hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to imidazole-based scaffolds through palladium-catalyzed cross-coupling reactions. Its stable hydrochloride salt form ensures excellent bench handling and solubility, while the bromine and amine functionalities offer orthogonal reactivity for downstream modifications. Functions effectively in Suzuki-Miyaura, Buchwald-Hartwig, and other standard transformations.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   43.84
  • LogP   1.1866
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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