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CS-W001157 4
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(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Ezetimibe Impurity

  • CAS No. 163222-33-1

  • Cat. No. CS-0167128
  • Purity≥98%
  • MDL No.MFCD00937872

*For research and further manufacturing use only, not for direct human use.

(3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Ezetimibe Impurity|CS-0167128

Structure of 163222-33-1

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General Information

  • CAS No. 163222-33-1
  • Cat. No. CS-0167128
  • Purity ≥98%
  • MDL No. MFCD00937872
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₂₁F₂NO₃
  • Molecular Weight 409.43
  • Synonym(s) None
  • SMILES O[C@H](C1=CC=C(C=C1)F)CC[C@@H]2[C@](C3=CC=C(C=C3)O)([H])N(C4=CC=C(C=C4)F)C2=O

Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standardsThese Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Synthesis

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    References

    • TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC. Patent: WO2008/151324 A1, 2008 ; Location in patent: Page/Page column 18 ;
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    References

    • Sniezek, Marcin; Stecko, Sebastian; Panfil, Irma; Furman, Bartlomiej; Chmielewski, Marek Journal of Organic Chemistry, 2013 , vol. 78, # 14 p. 7048 - 7057
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    • In-stock
      (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Ezetimibe Impurity|CS-0167128
      163222-33-1

    References

    • WO2009/140932 A2, ; Page/Page column 10-11 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H319-H372-H410
Precautionary Statements : P260-P264-P270-P273-P280-P330-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   60.77
  • LogP   4.8883
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   6

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