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CS-W001157 4
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Thiazolidine-2-carboxylic acid

  • CAS No. 16310-13-7

  • Cat. No. CS-0204253
  • Purity≥95%
  • MDL No.MFCD00068005

*For research and further manufacturing use only, not for direct human use.

Thiazolidine-2-carboxylic acid|CS-0204253

Structure of 16310-13-7

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General Information

  • CAS No. 16310-13-7
  • Cat. No. CS-0204253
  • Purity ≥95%
  • MDL No. MFCD00068005
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NO₂S
  • Molecular Weight 133.17
  • Synonym(s) Tetrahydrothiazole-2-carboxylic Acid
  • SMILES O=C(O)C1SCCN1

Description

Thiazolidine-2-carboxylic acid features a stable heterocyclic scaffold with a carboxylic acid group at the 2-position, enabling direct integration into peptide synthesis. The thiazolidine ring imparts enhanced conformational rigidity and metabolic stability, making it valuable for bioactive molecule design. This compound serves as a key building block in medicinal chemistry and peptide-based drug discovery.

Application

Thiazolidine-2-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling the construction of heterocyclic motifs through well-established cyclization and functionalization pathways. Its inherent stability, combined with orthogonal reactivity of the thiazolidine ring and carboxylic acid group, facilitates straightforward derivatization for peptide mimetics and bioactive compound synthesis. Functions effectively in standard coupling and protection protocols, offering reliable performance in both solution-phase and solid-phase workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   -0.2665
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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