(R)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate

Name: (R)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1629229-82-8
Cat. No. CS-0162178
Purity≥98%
MDL No.MFCD28969589

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(R)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate|CS-0162178

Structure of 1629229-82-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1629229-82-8
Cat. No. CS-0162178
Purity ≥98%
MDL No. MFCD28969589
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₈N₂O₃
Molecular Weight 214.26
Synonym(s) tert-butyl (2R)-2-methyl-3-oxopiperazine-1-carboxylate
SMILES O=C(N1[C@H](C)C(NCC1)=O)OC(C)(C)C

Description

(R)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate is a chiral piperazine scaffold featuring a stereodefined (R)-configuration at the C2 position. The molecule bears a ketone at C3 and a tert-butyloxycarbonyl (Boc) group, enabling selective derivatization. This stable, bench-ready building block integrates efficiently into complex heterocycles for medicinal chemistry applications.

Application

(R)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate serves as a versatile chiral building block for the synthesis of piperazine-based pharmaceutical intermediates. Its well-defined stereochemistry and stable tert-butyl carbamate handle enable straightforward functionalization, while the 3-oxo group facilitates nucleophilic addition and ring expansion reactions. The molecule exhibits excellent bench stability and compatibility with standard purification protocols, making it ideal for iterative synthetic sequences in medicinal chemistry and process development workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 58.64
LogP 0.7418
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aliphatic heterocycle compounds Piperazine compounds

Key Words

1629229-82-8 sigma1629229-82-8 manufacturer1629229-82-8 price1629229-82-8 structure1629229-82-8 SDSbuy 1629229-82-81629229-82-8 supplier1629229-82-8 uses1629229-82-8 molecular weightprice of 1629229-82-81629229-82-8 chemical name formula of 1629229-82-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(R)-tert-Butyl 2-methyl-3-oxopiperazine-1-carboxylate

CAS No. 1629229-82-8

Recommended Products