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CS-W001157 4
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2-Hydroxyethane-1-sulfonamide

  • CAS No. 162894-76-0

  • Cat. No. CS-0169345
  • Purity≥97%
  • MDL No.MFCD09029135

*For research and further manufacturing use only, not for direct human use.

2-Hydroxyethane-1-sulfonamide|CS-0169345

Structure of 162894-76-0

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General Information

  • CAS No. 162894-76-0
  • Cat. No. CS-0169345
  • Purity ≥97%
  • MDL No. MFCD09029135
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂H₇NO₃S
  • Molecular Weight 125.15
  • Synonym(s) 2-Hydroxyethanesulfonamide
  • SMILES O=S(CCO)(N)=O

Description

2-Hydroxyethane-1-sulfonamide features a sulfonamide group appended to a hydroxyethyl scaffold, delivering enhanced solubility and metabolic stability. This structure integrates a polar functional handle suitable for conjugation or derivatization in bioconjugate chemistry and drug discovery applications.

Application

2-Hydroxyethane-1-sulfonamide serves as a versatile sulfonamide building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide mimetics. Its hydroxyl and sulfonamide functionalities provide orthogonal reactivity for conjugation and derivatization, while offering excellent bench stability and solubility. The compound facilitates efficient functional group interconversions in multi-step syntheses, particularly useful in scaffold diversification and lead optimization workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

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Computational Chemistry Data

  • TPSA   80.39
  • LogP   -1.7328
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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