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CS-W001157 4
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1,2-Diphenylbutan-1-one

  • CAS No. 16282-16-9

  • Cat. No. CS-0152614
  • Purity≥98%
  • MDL No.MFCD00010344

*For research and further manufacturing use only, not for direct human use.

1,2-Diphenylbutan-1-one|CS-0152614

Structure of 16282-16-9

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General Information

  • CAS No. 16282-16-9
  • Cat. No. CS-0152614
  • Purity ≥98%
  • MDL No. MFCD00010344
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₆O
  • Molecular Weight 224.30
  • Synonym(s) 1,2-Diphenyl-1-butanone
  • SMILES CCC(C1=CC=CC=C1)C(=O)C2=CC=CC=C2

Description

3-(N-Morpholino)propanesulfonic Acid, Na; an analog to MES used in polyacrylamide gel electrophoresis.

Application

1,2-Diphenylbutan-1-one serves as a versatile synthetic intermediate in organic synthesis, enabling efficient construction of chiral benzylic systems. Its α-dicarbonyl-like reactivity facilitates nucleophilic additions and cyclization cascades, particularly in the formation of substituted indanes and related heterocyclic scaffolds. The molecule exhibits good bench stability and is compatible with standard purification techniques, making it suitable for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      36854-57-6
    • null|null
      2847-57-6
    • ~25%
    • In-stock
      1,2-Diphenylbutan-1-one|CS-0152614
      16282-16-9
    • null|null
      1118-46-3

    References

    • Lo Fiego, Marcos J.; Badajoz, Mercedes A.; Domini, Claudia; Chopa, Alicia B.; Lockhart, Maria T. Ultrasonics Sonochemistry, 2013 , vol. 20, # 3 p. 826 - 832
  • Route2
    • In-stock
      2-Phenylacetophenone|CS-0019389
      451-40-1
    • null|null
      75-03-6
    • ~%
    • In-stock
      1,2-Diphenylbutan-1-one|CS-0152614
      16282-16-9

    References

    • Journal of Medicinal Chemistry, , vol. 25, # 9 p. 1070 - 1077
  • Route3
    • null|null
      108-86-1
    • null|null
      495-40-9
    • ~56%
    • In-stock
      1,2-Diphenylbutan-1-one|CS-0152614
      16282-16-9
    • null|null
      2491-41-0

    References

    • Tetrahedron, , vol. 57, # 28 p. 5967 - 5974

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   4.0631
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   4

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