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CS-W001157 4
Total: USD 88.00

6-(tert-Butyl)-2,3-dihydro-1H-inden-1-one

  • CAS No. 162752-17-2

  • Cat. No. CS-0059179
  • Molecule weight188.27
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-(tert-Butyl)-2,3-dihydro-1H-inden-1-one|CS-0059179

Structure of 162752-17-2

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General Information

  • CAS No. 162752-17-2
  • Cat. No. CS-0059179
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₆O
  • Molecular Weight 188.27
  • Synonym(s) 6-(2,2-Dimethylpropyl)-1-indanone
  • SMILES O=C1CCC2=C1C=C(C(C)(C)C)C=C2

Description

6-(tert-Butyl)-2,3-dihydro-1H-inden-1-one is a sterically hindered indanone derivative featuring a bulky tert-butyl group at the 6-position. This substitution enhances stability and modulates reactivity in synthetic transformations. The molecule integrates readily into complex scaffolds due to its electron-rich aromatic system and functionalized carbonyl site, enabling efficient coupling reactions under mild conditions.

Application

6-(tert-Butyl)-2,3-dihydro-1H-inden-1-one serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted indane and indenone frameworks. Its tert-butyl group enhances steric bulk and bench stability, while the ketone functionality facilitates nucleophilic additions, reductions, and enolate-mediated transformations. This compound functions reliably in standard coupling and cyclization protocols, supporting scalable synthesis of complex heterocycles and pharmaceutical intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P261-P302+P352

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   3.113
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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