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CS-W001157 4
Total: USD 88.00

1,6-Dimethylpyrimidine-2,4(1H,3H)-dione

  • CAS No. 1627-27-6

  • Cat. No. CS-0698353
  • Purity≥98%
  • MDL No.MFCD00456725

*For research and further manufacturing use only, not for direct human use.

1,6-Dimethylpyrimidine-2,4(1H,3H)-dione|CS-0698353

Structure of 1627-27-6

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General Information

  • CAS No. 1627-27-6
  • Cat. No. CS-0698353
  • Purity ≥98%
  • MDL No. MFCD00456725
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O₂
  • Molecular Weight 140.14
  • Synonym(s) None
  • SMILES CN1C(C)=CC(=O)NC1=O

Description

1,6-Dimethylpyrimidine-2,4(1H,3H)-dione features a symmetric diketone core with methyl substituents at the 1 and 6 positions, enhancing stability and solubility in polar solvents. This scaffold serves as a key building block in heterocyclic synthesis, particularly for pyrimidine-based pharmaceutical intermediates. The molecule exhibits robust bench stability under standard conditions, facilitating straightforward handling in synthetic workflows.

Application

1,6-Dimethylpyrimidine-2,4(1H,3H)-dione serves as a stable, bench-ready building block for heterocyclic synthesis. Its dimethyl-substituted pyrimidinedione core exhibits predictable reactivity in nucleophilic substitution and condensation reactions, enabling efficient access to functionalized pyrimidine scaffolds. The molecule demonstrates excellent solubility in common organic solvents and tolerates a range of functional groups, facilitating straightforward purification and integration into multi-step synthetic sequences.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

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Computational Chemistry Data

  • TPSA   54.86
  • LogP   -0.61798
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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