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Structure of 16257-83-3
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(2S,4S)-4-Aminopyrrolidine-2-carboxylic acid is a stereochemically defined pyrrolidine derivative featuring a primary amine at the C4 position and a carboxylic acid at C2. This configuration imparts enhanced conformational rigidity and hydrogen-bonding capacity, making it a valuable scaffold in medicinal chemistry for targeting G-protein-coupled receptors and enzyme active sites. The compound exhibits favorable solubility and stability under standard biological conditions.
(2S,4S)-4-Aminopyrrolidine-2-carboxylic acid serves as a privileged scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through established coupling and cyclization protocols. Its stereochemically defined structure provides enhanced conformational rigidity and metabolic stability, facilitating efficient incorporation into peptide mimetics and kinase inhibitors. The molecule exhibits excellent bench stability, tolerates diverse functional groups, and simplifies purification due to its zwitterionic character at physiological pH.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: