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(1R,3R)-3-Aminocyclopentanecarboxylic acid hydrochloride

  • CAS No. 1625682-44-1

  • Cat. No. CS-0058718
  • Molecule weight165.62
  • Purity≥97%
  • MDL No.MFCD27989239

*For research and further manufacturing use only, not for direct human use.

(1R,3R)-3-Aminocyclopentanecarboxylic acid hydrochloride|CS-0058718

Structure of 1625682-44-1

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General Information

  • CAS No. 1625682-44-1
  • Cat. No. CS-0058718
  • Purity ≥97%
  • MDL No. MFCD27989239
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO₂
  • Molecular Weight 165.62
  • Synonym(s) (1R,3R)-3-AMINOCYCLOPENTANECARBOXYLIC ACID HCL
  • SMILES N[C@H]1C[C@H](C(O)=O)CC1.Cl

Description

(1R,3R)-3-Aminocyclopentanecarboxylic acid hydrochloride is a stereochemically defined cyclic amino acid derivative featuring a rigid cyclopentane scaffold with adjacent amine and carboxylic acid functionalities. This configuration enhances its utility in peptide-based drug discovery, where conformational restraint improves target binding affinity and metabolic stability. The hydrochloride salt form ensures enhanced solubility and handling convenience under standard laboratory conditions.

Application

(1R,3R)-3-Aminocyclopentanecarboxylic acid hydrochloride serves as a stereochemically defined building block for bioactive heterocycles and peptidomimetics. Its rigid cyclopentane core provides conformational constraint, while the protected amine and carboxylic acid functionalities enable versatile coupling reactions. The hydrochloride salt enhances bench stability and solubility, facilitating handling in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.6202
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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