(R)-3-Phenylmorpholine hydrochloride

Name: (R)-3-Phenylmorpholine hydrochloride
Brand: ChemScene
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CAS No. 1624261-27-3
Cat. No. CS-0198261
Purity≥98%
MDL No.MFCD12910599

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-3-Phenylmorpholine hydrochloride|CS-0198261

Structure of 1624261-27-3

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General Information

CAS No. 1624261-27-3
Cat. No. CS-0198261
Purity ≥98%
MDL No. MFCD12910599
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₄ClNO
Molecular Weight 199.68
Synonym(s) (R)-3-phenylmorpholine HCl
SMILES C1([C@@H]2COCCN2)=CC=CC=C1.Cl

Description

(R)-3-Phenylmorpholine hydrochloride is a chiral heterocyclic compound featuring a phenyl-substituted morpholine core with defined stereochemistry at the 3-position. This bench-stable salt form enhances solubility and handling in synthetic workflows, enabling efficient integration into asymmetric synthesis and medicinal chemistry campaigns requiring precise stereocontrol.

Application

(R)-3-Phenylmorpholine hydrochloride serves as a stereochemically defined heterocyclic building block, enabling efficient access to chiral pharmacophores in medicinal chemistry. Its morpholine core exhibits favorable solubility and metabolic stability, while the phenyl substituent enhances π-stacking potential in target binding. The hydrochloride salt ensures excellent bench stability and ease of handling, facilitating straightforward purification and compatibility with standard coupling and functionalization protocols in multi-step syntheses.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 21.26
LogP 1.7693
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

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(R)-3-Phenylmorpholine hydrochloride

CAS No. 1624261-27-3

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