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CS-W001157 4
Total: USD 88.00

1-Boc-3-aminomethyl-piperidine

  • CAS No. 162167-97-7

  • Cat. No. CS-D0643
  • Purity≥97%
  • MDL No.MFCD01317792

*For research and further manufacturing use only, not for direct human use.

1-Boc-3-aminomethyl-piperidine|CS-D0643

Structure of 162167-97-7

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General Information

  • CAS No. 162167-97-7
  • Cat. No. CS-D0643
  • Purity ≥97%
  • MDL No. MFCD01317792
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₂N₂O₂
  • Molecular Weight None
  • Synonym(s) Tert-butyl 3-(aminomethyl)piperidine-1-carboxylate
  • SMILES O=C(OC(C)(C)C)N(CCC1)CC1CN

Description

1-Boc-3-aminomethyl-piperidine features a protected amine group enabling stable incorporation into complex molecular architectures. The piperidine core provides a rigid, nitrogen-rich scaffold ideal for medicinal chemistry applications. This derivative offers enhanced solubility and reduced basicity compared to the free amine, simplifying purification and handling during synthesis workflows.

Application

1-Boc-3-aminomethyl-piperidine serves as a versatile building block in medicinal chemistry, enabling efficient access to piperidine-based scaffolds. The Boc group provides excellent stability and orthogonal protection, facilitating selective deprotection during late-stage functionalization. It reacts reliably with electrophiles and participates in standard coupling protocols, offering high compatibility with diverse reaction conditions and purification workflows common in API synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS09
Signal Word : Warning
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H319-H410
Precautionary Statements : P264-P270-P273-P280-P330-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   1.5922
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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