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CS-W001157 4
Total: USD 88.00

(3,4-Difluorophenyl)hydrazine

  • CAS No. 161886-22-2

  • Cat. No. CS-0268928
  • Purity95+%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3,4-Difluorophenyl)hydrazine|CS-0268928

Structure of 161886-22-2

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General Information

  • CAS No. 161886-22-2
  • Cat. No. CS-0268928
  • Purity 95+%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆F₂N₂
  • Molecular Weight 144.12
  • Synonym(s) Hydrazine, (3,4-difluorophenyl)- (9CI)
  • SMILES C1=CC(=C(C=C1NN)F)F

Synthesis

  • Route1
    • 3,4-Difluoroaniline Gefitinib Impurity|CS-0167147
      3863-11-4
    • ~56%
    • (3,4-Difluorophenyl)hydrazine|CS-0268928
      161886-22-2

    References

    • TAKEDA PHARMACEUTICAL COMPANY LIMITED; BROWN, Jason, W.; KEUNG, Walter; LI, Zhe; TYHONAS, John Patent: WO2010/111634 A2, 2010 ; Location in patent: Page/Page column 127 ; WO 2010/111634 A2
  • Route2

    References

    • Abbott Laboratories Patent: US6307047 B1, 2001 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   1.2504
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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