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Structure of 161609-89-8
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3-(Piperidin-4-yl)pyridine features a pyridine ring linked to a piperidine moiety, creating a versatile scaffold with enhanced solubility and basicity. This configuration supports hydrogen bonding and π-stacking interactions, enabling effective integration into pharmaceutical intermediates and ligands for metal coordination. The molecule exhibits bench-stable behavior under standard conditions.
3-(Piperidin-4-yl)pyridine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyridine core provides strong hydrogen-bonding capacity and favorable pharmacokinetic properties, while the piperidinyl moiety offers tunable basicity and metabolic stability. The compound exhibits excellent bench stability, facilitates efficient purification via crystallization or chromatography, and demonstrates broad compatibility with common reaction conditions, making it a reliable scaffold for lead optimization in drug discovery programs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: