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Structure of 1613-88-3
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4-Chloro-N-hydroxybenzamide features a hydroxylamine moiety appended to a chlorinated aromatic ring, enabling direct engagement in nitration and amidation transformations. This bench-stable derivative integrates readily into synthetic sequences requiring electrophilic activation or O-acylation pathways.
4-Chloro-N-hydroxybenzamide serves as a versatile intermediate in the synthesis of heterocyclic scaffolds and functionalized aryl amides. Its combination of a chloro substituent and N-hydroxy group enables selective coupling reactions, including palladium-catalyzed cross-couplings and oxime derivatization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: