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Structure of 1612172-50-5
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4-(Trifluoromethoxy)piperidine hydrochloride features a trifluoromethoxy group attached to a piperidine core, conferring enhanced lipophilicity and metabolic stability. This bench-stable salt form improves solubility and handling in synthetic workflows. The compound serves as a key building block in medicinal chemistry for developing CNS-targeted therapeutics and bioactive molecules requiring optimized membrane permeability.
4-(Trifluoromethoxy)piperidine hydrochloride serves as a versatile building block in medicinal chemistry, enabling the introduction of a lipophilic trifluoromethoxy group at the piperidine nitrogen. The hydrochloride salt enhances solubility and stability, facilitating handling and purification. It participates reliably in nucleophilic substitution and reductive amination reactions, supporting the construction of diverse heterocyclic scaffolds relevant to CNS-targeted therapeutics and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: