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CS-W001157 4
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2-(3',3'-Dimethyl-6-nitrospiro[chromene-2,2'-indolin]-1'-yl)ethanol

  • CAS No. 16111-07-2

  • Cat. No. CS-0153805
  • Purity≥95%
  • MDL No.MFCD00369031

*For research and further manufacturing use only, not for direct human use.

2-(3',3'-Dimethyl-6-nitrospiro[chromene-2,2'-indolin]-1'-yl)ethanol|CS-0153805

Structure of 16111-07-2

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General Information

  • CAS No. 16111-07-2
  • Cat. No. CS-0153805
  • Purity ≥95%
  • MDL No. MFCD00369031
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₀N₂O₄
  • Molecular Weight 352.38
  • Synonym(s) 1-(2-Hydroxyethyl)-3,3-Dimethyl-6-Nitrospiro[1(2H)-Benzopyran-2,2-Indoline]
  • SMILES CC1(C)C2=CC=CC=C2N(CCO)C31C=CC4=CC(=CC=C4O3)[N+](=O)[O-]

Description

This spirocyclic chromene-indoline compound integrates a nitro-substituted chromene moiety with a pendant ethanol handle, enabling straightforward derivatization. The dimethyl substitution enhances steric shielding and stability, while the electron-deficient nitro group facilitates photoreactivity under UV irradiation. Designed for use in photoresponsive materials and molecular switches.

Synthesis

  • Route1
    • null|null
      36508-00-6
    • In-stock
      5-Nitrosalicylaldehyde|CS-M1907
      97-51-8
    • ~80%
    • In-stock
      2-(3',3'-Dimethyl-6-nitrospiro[chromene-2,2'-indolin]-1'-yl)ethanol|CS-0153805
      16111-07-2

    References

    • Raymo; Giordani Journal of the American Chemical Society, 2001 , vol. 123, # 19 p. 4651 - 4652
  • Route2

    References

    • Natali, Manuel; Giordani, Silvia Organic and Biomolecular Chemistry, 2012 , vol. 10, # 6 p. 1162 - 1171
  • Route3

    References

    • Zhu, Ming-Qiang; Zhang, Guo-Feng; Hu, Zhe; Aldred, Matthew P.; Li, Chong; Gong, Wen-Liang; Chen, Tao; Huang, Zhen-Li; Liu, Shiyong Macromolecules, 2014 , vol. 47, # 5 p. 1543 - 1552

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P260-P261-P264-P271-P280-P302+P352-P304+P340-P340-P362-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.84
  • LogP   3.4868
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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