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CS-W001157 4
Total: USD 88.00

2-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride

  • CAS No. 1610028-42-6

  • Cat. No. CS-W006960
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride|CS-W006960

Structure of 1610028-42-6

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General Information

  • CAS No. 1610028-42-6
  • Cat. No. CS-W006960
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈Cl₂N₂
  • Molecular Weight 213.15
  • Synonym(s) None
  • SMILES CN1CC2(CCNCC2)C1.Cl.Cl

Description

2-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride is a rigid, bicyclic amine scaffold featuring a spirocyclic core with strategically positioned nitrogen atoms. This configuration imparts high basicity and enhanced solubility in polar solvents, enabling efficient incorporation into medicinal chemistry libraries. The dihydrochloride salt form ensures stability and ease of handling under standard laboratory conditions.

Application

2-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride serves as a rigid, bicyclic scaffold enabling precise spatial orientation in medicinal chemistry. Its diazaspirocore exhibits enhanced metabolic stability and favorable solubility, while the protonated amine centers facilitate salt formation and improve handling. Functions effectively in ligand design for GPCRs and kinase targets, with compatibility across standard coupling and functionalization protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   1.1452
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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