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CS-W001157 4
Total: USD 88.00

5-Imino-2,5-dihydro-1H-pyrazol-3-amine

  • CAS No. 16082-33-0

  • Cat. No. CS-0060291
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Imino-2,5-dihydro-1H-pyrazol-3-amine|CS-0060291

Structure of 16082-33-0

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General Information

  • CAS No. 16082-33-0
  • Cat. No. CS-0060291
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆N₄
  • Molecular Weight 98.11
  • Synonym(s) 3,5-Diamino-1H-pyrazole
  • SMILES NC1=NNC(N)=C1

Description

5-Imino-2,5-dihydro-1H-pyrazol-3-amine is a nitrogen-rich heterocyclic scaffold featuring a conjugated imino group and a primary amine, enabling versatile coordination in metal complexes. This bench-stable, moisture-tolerant core integrates readily into ligand design for catalysis and functional materials.

Application

5-Imino-2,5-dihydro-1H-pyrazol-3-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of pyrazole-based scaffolds through standard functionalization protocols. Its imino and amino groups provide orthogonal reactivity for coupling, cyclization, and derivatization, facilitating access to diverse pharmacophores. The compound exhibits good bench stability and compatibility with common reaction conditions, supporting efficient purification and scalability in synthetic workflows.

Synthesis

  • Route1
    • null|null
      26315-24-2
    • ~%
    • In-stock
      5-Imino-2,5-dihydro-1H-pyrazol-3-amine|CS-0060291
      16082-33-0

    References

    • US2007/82902 A1, ; Page/Page column 18 ; US 20070082902 A1
  • Route2
    • null|null
      109-77-3
    • ~%
    • In-stock
      5-Imino-2,5-dihydro-1H-pyrazol-3-amine|CS-0060291
      16082-33-0

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. <2> 52, p. 37

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   80.72
  • LogP   -0.4259
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   0

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