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CS-W001157 4
Total: USD 88.00

4-Isopropylbenzenesulfonic acid

  • CAS No. 16066-35-6

  • Cat. No. CS-0094251
  • Purity≥97%
  • MDL No.MFCD00137273
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Isopropylbenzenesulfonic acid|CS-0094251

Structure of 16066-35-6

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Description

4-Isopropylbenzenesulfonic acid offers a robust sulfonic acid functionality appended to an aromatic ring bearing a sterically hindered isopropyl group. This structural arrangement enhances solubility in organic media while maintaining strong acidity and thermal stability under standard reaction conditions. The compound serves as a potent, bench-stable catalyst in electrophilic substitutions and acid-promoted rearrangements.

Application

4-Isopropylbenzenesulfonic acid serves as a robust, bench-stable Brønsted acid catalyst in organic synthesis. Its aryl sulfonic acid functionality enables efficient protonation, esterification, and electrophilic substitution reactions with high functional group tolerance. The isopropyl substituent enhances solubility in organic media while maintaining strong acidity, making it particularly effective in scale-up applications and catalytic transformations requiring mild to moderate acidic conditions.

General Information

  • CAS No. 16066-35-6
  • Cat. No. CS-0094251
  • Purity ≥97%
  • MDL No. MFCD00137273
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O₃S
  • Molecular Weight 200.25
  • Synonym(s) 4-(propan-2-yl)benzene-1-sulfonic acid
  • SMILES O=S(C1=CC=C(C(C)C)C=C1)(O)=O

Computational Chemistry Data

  • TPSA   54.37
  • LogP   2.0567
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2585
Class : 8
Packing Group :
Hazard Statements : H302+H312+H332-H314
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501

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