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CS-W001157 4
Total: USD 88.00

4-Guanidinobenzoic acid

  • CAS No. 16060-65-4

  • Cat. No. CS-0185073
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Guanidinobenzoic acid|CS-0185073

Structure of 16060-65-4

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Description

4-Guanidinobenzoic acid features a para-guanidino group appended to a benzoic acid scaffold, delivering high solubility and strong hydrogen-bonding capacity. This combination enables effective integration into peptide conjugates and bioactive molecules, enhancing target affinity and stability under physiological conditions.

Application

4-Guanidinobenzoic acid serves as a versatile building block for bioactive molecule synthesis, enabling direct incorporation of both carboxylic acid and guanidine functionalities. Its stability under standard reaction conditions facilitates straightforward derivatization, including amide formation and salt selection for solubility optimization. The compound functions effectively in peptide conjugation and heterocycle construction, offering reliable performance in medicinal chemistry campaigns targeting kinase inhibitors and enzyme modulators.

General Information

  • CAS No. 16060-65-4
  • Cat. No. CS-0185073
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉N₃O₂
  • Molecular Weight 179.18
  • Synonym(s) 4-guanidinobenzoate
  • SMILES O=C(O)C1=CC=C(NC(N)=N)C=C1

Computational Chemistry Data

  • TPSA   99.2
  • LogP   0.69017
  • H_Acceptors   2
  • H_Donors   4
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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