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Structure of 16034-48-3
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1H-pyrazol-1-ylacetic acid features a pyrazole ring directly linked to a carboxylic acid-bearing acetyl side chain, enabling versatile conjugation in medicinal chemistry. This scaffold integrates readily into bioactive molecules, offering enhanced solubility and metabolic stability compared to simpler aryl analogs.
1H-pyrazol-1-ylacetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrazole-based scaffolds through standard amide coupling and alkylation protocols. Its stability under routine reaction conditions and compatibility with diverse functional groups facilitate efficient access to bioactive molecules. The carboxylic acid moiety provides a handle for derivatization, while the pyrazole ring offers structural rigidity and hydrogen-bonding potential, making it a practical choice for lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: