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CS-W001157 4
Total: USD 88.00

Tetramethylene sulfoxide

  • CAS No. 1600-44-8

  • Cat. No. CS-0207394
  • Purity≥96%
  • MDL No.MFCD00005477

*For research and further manufacturing use only, not for direct human use.

Tetramethylene sulfoxide|CS-0207394

Structure of 1600-44-8

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General Information

  • CAS No. 1600-44-8
  • Cat. No. CS-0207394
  • Purity ≥96%
  • MDL No. MFCD00005477
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈OS
  • Molecular Weight 104.17
  • Synonym(s) TetrahydrothiopheneSoxide
  • SMILES C1CCS(=O)C1

Description

Aminoethyl-SS-propionic acid is a cleavable compound containing a terminal amine and carboxylic acid group. The disulfide bonds can be cleaved using Dithiothreitol (DTT) reagent. The terminal amine can be reacted with carboxylic acid, activated NHS esters and other carbonyl compounds. The terminal carboxylic acid can be reacted with primary amines in the presence of activators such as EDC and HATU to form a stable amide bond.

Synthesis

  • Route1
    • null|null
      110-01-0
    • ~99%
    • In-stock
      Tetramethylene sulfoxide|CS-0207394
      1600-44-8

    References

    • Ali, Mohammed Hashmat; Bohnert, Gary J. Synthesis, 1998 , # 9 p. 1238 - 1240
  • Route2
    • null|null
      110-01-0
    • ~65%
    • In-stock
      Tetramethylene sulfoxide|CS-0207394
      1600-44-8
    • null|null
      102244-56-4

    References

    • Tetrahedron Letters, , vol. 26, # 38 p. 4609 - 4612
  • Route3
    • null|null
      110-01-0
    • ~87%
    • In-stock
      Tetramethylene sulfoxide|CS-0207394
      1600-44-8
    • null|null
      126-33-0

    References

    • Organic Letters, , vol. 1, # 2 p. 189 - 191

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   0.5289
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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