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Structure of 159830-97-4
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This chiral pyrrolidine derivative features a hydroxyl group at C3 and a carboxylic acid at C2, stabilized as the hydrochloride salt. The stereochemistry at C2 and C3 enables precise integration into peptide mimetics and bioactive scaffolds. Bench-stable and moisture-tolerant, it serves as a key building block for medicinal chemistry campaigns targeting conformationally restricted ligands.
(2S,3R)-3-Hydroxypyrrolidine-2-carboxylic acid hydrochloride serves as a stereochemically defined building block for bioactive heterocycles and peptidomimetics. Its constrained pyrrolidine core with orthogonal hydroxyl and carboxylic acid functionalities enables direct incorporation into complex scaffolds via standard amide coupling, glycosylation, or metal-catalyzed transformations. The hydrochloride salt enhances bench stability and simplifies purification, facilitating scalable synthesis in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: