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CS-W001157 4
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(9H-Fluoren-9-yl)methyl 4-aminobenzylcarbamate

  • CAS No. 159790-81-5

  • Cat. No. CS-0149927
  • Purity≥95%
  • MDL No.MFCD06658452

*For research and further manufacturing use only, not for direct human use.

(9H-Fluoren-9-yl)methyl 4-aminobenzylcarbamate|CS-0149927

Structure of 159790-81-5

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General Information

  • CAS No. 159790-81-5
  • Cat. No. CS-0149927
  • Purity ≥95%
  • MDL No. MFCD06658452
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₀N₂O₂
  • Molecular Weight 344.41
  • Synonym(s) 4-(N-Fmoc-aminomethyl)aniline
  • SMILES NC=1C=CC(=CC1)CNC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O

Description

This fluorenylmethoxycarbonyl-protected amino acid derivative features a robust Cbz-like scaffold with a para-aminobenzylcarbamate handle, enabling efficient conjugation in peptide synthesis. The electron-rich fluorenyl moiety ensures high solubility and stability under standard conditions, while the primary amine facilitates orthogonal functionalization.

Synthesis

  • Route1

    References

    • Kuil, Joeri; van Wandelen, Loek T.M.; de Mol, Nico J.; Liskamp, Rob M.J. Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1393 - 1399

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   4.3075
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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