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CS-W001157 4
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3-Tosyl-6-oxa-3-azabicyclo[3.1.0]Hexane

  • CAS No. 159555-66-5

  • Cat. No. CS-0464083
  • Purity≥98%
  • MDL No.MFCD22575028

*For research and further manufacturing use only, not for direct human use.

3-Tosyl-6-oxa-3-azabicyclo[3.1.0]Hexane|CS-0464083

Structure of 159555-66-5

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General Information

  • CAS No. 159555-66-5
  • Cat. No. CS-0464083
  • Purity ≥98%
  • MDL No. MFCD22575028
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₃NO₃S
  • Molecular Weight 239.29
  • Synonym(s) 6-Oxa-3-azabicyclo[3.1.0]hexane, 3-[(4-Methylphenyl)sulfonyl]-
  • SMILES CC1=CC=C(C=C1)S(=O)(=O)N2CC3C(C2)O3

Synthesis

  • Route1

    References

    • Hodgson, David M.; Miles, Timothy J.; Witherington, Jason Tetrahedron, 2003 , vol. 59, # 49 p. 9729 - 9742
  • Route2
    • 1-Tosyl-2,3-dihydro-1H-pyrrole|CS-0724763
      130719-30-1
    • Sodium sulfate anhydrous, United States Pharmacopeia (USP) Reference Standard|CS-0909798
      7757-82-6
    • ~82%
    • 3-Tosyl-6-oxa-3-azabicyclo[3.1.0]Hexane|CS-0464083
      159555-66-5

    References

    • Bayer Aktiengesellschaft Patent: US6133260 A1, 2000 ;
  • Route3

    References

    • Unthank, Matthew G.; Hussain, Nigel; Aggarwal, Varinder K. Angewandte Chemie - International Edition, 2006 , vol. 45, # 42 p. 7066 - 7069

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.91
  • LogP   0.76672
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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