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Structure of 15861-30-0
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Indoline-5-carboxylic acid features a rigid, electron-rich indoline scaffold with a carboxylic acid group at the 5-position, enabling direct conjugation in peptide and heterocyclic syntheses. This bench-stable derivative integrates readily into bioactive molecule frameworks, offering enhanced solubility and metabolic stability in medicinal chemistry applications.
Indoline-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant heterocyclic scaffolds. Its functionality arises from the orthogonal reactivity of the indoline nitrogen and carboxylic acid group, facilitating amide coupling, derivatization, and cyclization reactions. The molecule exhibits good bench stability and is readily purified by standard techniques, making it well-suited for iterative synthesis and library generation in drug discovery workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: