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Structure of 1581683-57-9
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tert-Butyl 5-oxo-2-azaspiro[3.4]octane-2-carboxylate is a sterically shielded spirocyclic scaffold featuring a ketone at C5 and a protected amine at the bridgehead nitrogen. This bench-stable, moisture-tolerant building block enables direct incorporation of complex nitrogen-containing frameworks into medicinal chemistry libraries.
tert-Butyl 5-oxo-2-azaspiro[3.4]octane-2-carboxylate serves as a versatile spirocyclic building block for medicinal chemistry and natural product synthesis, enabling efficient access to nitrogen-containing heterocycles. Its enolizable ketone and protected amine functionality support diverse transformations including reductive amination, nucleophilic addition, and transition-metal-catalyzed coupling reactions. The tert-butyl ester group offers excellent bench stability and facile removal under mild acidic conditions, enhancing utility in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: