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CS-W001157 4
Total: USD 88.00

(S,R)-BisPh-propabBox

  • CAS No. 157825-96-2

  • Cat. No. CS-0087534
  • Purity≥95%
  • MDL No.MFCD30187376

*For research and further manufacturing use only, not for direct human use.

(S,R)-BisPh-propabBox|CS-0087534

Structure of 157825-96-2

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General Information

  • CAS No. 157825-96-2
  • Cat. No. CS-0087534
  • Purity ≥95%
  • MDL No. MFCD30187376
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₃H₃₀N₂O₂
  • Molecular Weight 486.60
  • Synonym(s) (4S,4'S,5R,5'R)-2,2'-(1-Methylethylidene)bis[4,5-dihydro-4,5-diphenyl-Oxazole
  • SMILES CC(C1=N[C@@H](C2=CC=CC=C2)[C@@H](C3=CC=CC=C3)O1)(C)C4=N[C@@H](C5=CC=CC=C5)[C@@H](C6=CC=CC=C6)O4

Description

(S,R)-BisPh-propabBox features a chiral bisphosphine scaffold with propyl-bridged aryl groups, delivering enhanced stereocontrol in asymmetric catalysis. This bench-stable ligand integrates readily into palladium and nickel systems, enabling efficient cross-coupling reactions under mild conditions.

Application

(S,R)-BisPh-propabBox serves as a robust chiral ligand in asymmetric catalysis, enabling high enantioselectivity in transition metal-catalyzed transformations. Its rigid bisphosphine architecture and propyl-bridged backbone enhance stability and facilitate efficient coordination with palladium and platinum centers. The ligand demonstrates excellent functional group tolerance and is well-suited for iterative cross-coupling reactions and stereoselective C–C bond formations in complex molecule synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   7.8352
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   6

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