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tert-Butyl 6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate

  • CAS No. 1569514-57-3

  • Cat. No. CS-0058575
  • Purity≥98%
  • MDL No.MFCD23115376

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate|CS-0058575

Structure of 1569514-57-3

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General Information

  • CAS No. 1569514-57-3
  • Cat. No. CS-0058575
  • Purity ≥98%
  • MDL No. MFCD23115376
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇N₃O₂
  • Molecular Weight 223.27
  • Synonym(s) tert-butyl 1,5,6,7-tetrahydropyrazolo[4,3-b]pyridine-4-carboxylate
  • SMILES O=C(OC(C)(C)C)N1C2=C(NN=C2)CCC1

Description

tert-Butyl 6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate features a fused pyrazolo-pyridine core with a reducible carbonyl at the 4-position, enabling downstream functionalization. This bench-stable, moisture-tolerant building block integrates readily into heterocyclic scaffolds for medicinal chemistry applications.

Application

tert-Butyl 6,7-dihydro-1H-pyrazolo[4,3-b]pyridine-4(5H)-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and synthetic organic applications. The protected pyrazolopyridine core exhibits robust bench stability and facilitates efficient functionalization at the C4 position. It enables straightforward deprotection to access bioactive scaffolds and participates reliably in palladium-catalyzed cross-coupling reactions, supporting diverse molecular architectures in drug discovery workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   58.22
  • LogP   2.0974
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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