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Structure of 1562338-69-5
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This pyridazine derivative features a chlorinated heterocyclic core paired with a sterically hindered tetramethylpiperidin-4-yloxy substituent, enhancing solubility and stability. The electron-deficient pyridazine ring enables selective coupling reactions in synthetic intermediates, while the bulky piperidine moiety reduces unwanted side reactivity. Designed for use in advanced medicinal chemistry and materials synthesis, it offers improved handling under standard conditions.
3-Chloro-6-(2,2,6,6-tetramethylpiperidin-4-yloxy)pyridazine serves as a versatile building block in medicinal chemistry, enabling the construction of pyridazinyl-containing scaffolds through palladium-catalyzed cross-coupling reactions. The chloropyridazine core exhibits high reactivity in Suzuki, Stille, and Buchwald–Hartwig transformations, while the sterically hindered tetramethylpiperidine group enhances solubility and metabolic stability. This compound offers excellent bench stability and facilitates efficient purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: